(Angioneurotic Edema)
Definition
Angioedema is a common condition that involves swelling beneath the surface of the skin with or without redness. Angioedema can occur around the eyelids and lips, or on the face, hands, feet, and genitalia. Since this condition can cause swelling of the airways, it is important that you seek medical care if you think you have angioedema.
Causes
Angioedema is often associated with urticaria (hives) . It can be caused by:
• Foods (eg, strawberries, pineapple, shellfish, nuts, alcohol)
• Food additives (eg, benzoates, dyes)
• Medications (eg, nonsteroidal anti-inflammatory drugs (NSAIDS) , ACE inhibitors, penicillin, aspirin, morphine)
• Infection
• Inhaled substances (eg, pollens, mold spores, animal dander)
• Certain diseases (eg, hyperthyroidism , cancer , rheumatic fever )
• Environment (eg, cold, heat, water)
• Skin contact with plants, animals, or medications
• Skin disease
• Genetic predisposition
Risk Factors
A risk factor is something that increases your chance of getting a disease or condition. The following risk factors increase your chance of developing angioedema. If you have any of these risk factors, tell your doctor:
• Age: 30-60 years old
• Gender: female
• Drinking alcohol
• Emotional stress
• Hyperthyroidism
• Taking nonsteroidal anti-inflammatory drugs
• Menstruation
Symptoms
If you experience any of these symptoms do not assume it is due to angioedema. These symptoms may be caused by other health conditions. If you experience any one of them, see your physician.
• Large swellings with indistinct borders around the eyelids and lips
• Lesions on the face, trunk, genitalia, and extremities
• Swelling of the hands and feet
• Swelling of the throat
• Abdominal pain
• Generalized rash that isn’t itchy
Diagnosis
Your doctor will ask about your symptoms and medical history, and perform a physical exam. Tests may include the following:
• Blood Tests
• Urine Tests
• Skin Tests
• Throat Culture
• Stool Sample
• Abdominal Ultrasound –a test that uses sound waves to examine the abdomen
Treatment
Talk with your doctor about the best treatment plan for you. Minor episodes of angioedema may need no treatment, but it is important to make sure the swelling does not spread to the airway, which can be life-threatening. Treatment options include the following:
Medications
Certain medications (eg, antihistamines, epinephrine, corticosteroids, and pain medications) may help ease symptoms of angioedema.
Tracheostomy
If your airway is affected, your doctor may place a tube in your throat to keep your airway open.
Prevention
To help reduce your chances of developing this condition, avoid substances or triggers that have brought on hives or angioedema in the past.
